Endoscopic Manifestations and Mucosal Patterns Associated to Collagenous Colitis
نویسندگان
چکیده
Microscopic colitis (MC) are clinical pathologic entities characterized by secretory-like aqueous chronic diarrhea, in its large majority without hematochezia. From the first descriptions of MC1, normal endoscopic and radiological findings have been a pathognomonic feature. It is thought that up to 20% of adults with chronic diarrhea who have an endoscopically normal colonoscopy may have MC. Most common MC are collagenous colitis and lymphocytic colitis. They are two morphologically distinct entities of MC. They are similar in presentation but differ histologically. Endoscopic biopsy is required for the diagnosis of MC2. As there are usually no mucosal abnormalities, the biopsies taken must be random. However, several authors have described different mucosal abnormalities related to the MC, most of them related to collagenous colitis. Our aims were to review the medical literature and to describe the mucosal patterns and mucosal abnormalities that have been associated with the microscopic colitis, especially those related to the collagenous colitis.
منابع مشابه
Linear mucosal defects: a characteristic endoscopic finding of lansoprazole-associated collagenous colitis.
copathologic entity characterized by chronic watery diarrhea and, histologically, by the subepithelial deposition of collagen [1,2]. Some luminal antigens, including nonsteroidal anti-inflammatory drugs (NSAIDs) and proton pump inhibitors (PPIs), particularly lansoprazole, are thought to contribute to the development of collagenous colitis. On endoscopy, collagenous colitis usually shows no orm...
متن کاملFrequency and Distribution of Microscopic Findings in Patients with Chronic Non-Bloody Diarrhea and Normal Colonoscopy
Background: Chronic diarrhea is a common problem in patients with symptoms related to gastro-intestinal tract. Some of these patients present with chronic non-bloody, watery diarrhea and no specific clinical, laboratory, or endoscopic findings. The aim of the present study was to investigate the value of histological findings in patients with chronic diarrhea who have normal or non-specific end...
متن کاملMucosal tears during colonoscopy in a patient with ulcerative colitis.
of bloody diarrhea. Except for partial gastroduodenectomy because of a duodenal ulcer, the subject was healthy and was not taking any regular medication. He had not recently visited any foreign countries. Physical examination was unremarkable. Routine laboratory tests and complete blood analysis were normal. Total colonoscopy was performed after standard bowel preparation, without sedation. Col...
متن کاملMucosal atrophy in collagenous colitis: a case report
BACKGROUND Mucosal atrophy as a potential cause of impaired colonic compliance has not yet been described as a complication in Collagenous Colitis (CC). CASE PRESENTATION We present a 51-year-old female patient with a 20-year history of diarrhea and diagnosed with CC ten years prior to her presentation. We reviewed reports from three colonoscopies performed after the diagnosis. Overall 12 bio...
متن کامل